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It may be necessary to stay on Zy-b-an for a longer period, depending upon the rapidity with which you withdraw from nicotine. Provides effects side tmj zyban product or service and how long should i take zyban. Zy-b-an helps reduce withdrawal symptoms as you remove cigarettes from your life. It s important to remain on Zy-b-an for at least 7 to 12 weeks but it may require up to 6 months of therapy if your dependence on nicotine is great. WHEN SHOULD I STOP SMOKING. Provides effects side tmj zyban product or service and how long should i take zyban.