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Unlike over-the-counter wrinkle creams that simply exfoliate the surface layer of skin, Ren ova is believed to work on all layers of the skin, including the epidermis, where pigmentary changes occur and even the deeper portions of the skin where fine wrinkling is thought to begin. Provides buy renova product or service and renova information. Researchers believe this is one way that Ren ova reduces the signs of aging. HOW EFFECTIVE IS Ren ova: In clinical studies looking at the efficacy of Ren ova 60% of patients treated for 24 weeks saw at least some decrease in fine facial wrinkling. The effect on coarse facial wrinkling, mottled hyperpigmentation, skin roughness, and laxity of the facial skin were less clear since the effect seen on each patient varied from study to study. Provides buy renova product or service and renova information.